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Year 12 Science Biology

Immunology & Vaccines

The immune system is one of the most sophisticated biological systems in the human body. Understanding how vaccines harness immune memory has become especially relevant in a post-pandemic world, and underpins careers in medicine, pharmacology, and public health.

What You Need to Know

Key Concept Diagram

The immune system has two lines of defence: innate (non-specific, fast) and adaptive (specific, slower but memorises)

B lymphocytes produce antibodies that neutralise specific pathogens; T cells kill infected cells

Immunological memory: after first exposure, memory cells remain — enabling rapid response upon re-exposure

Vaccines use antigens (weakened/killed pathogens, subunits, or mRNA) to generate immunity without causing disease

Key Vocabulary

antibody

A protein produced by B cells that specifically binds to and neutralises a pathogen

antigen

A molecule (usually on a pathogen's surface) that triggers an immune response

immunological memory

The ability of the immune system to respond faster and more effectively upon repeated exposure to the same pathogen

mRNA vaccine

A vaccine that delivers messenger RNA instructions for cells to produce an antigen, triggering an immune response

Knowledge Check

Select the correct answer for each question. Click "Check Answer" to see if you are right.

Question 1

Which cells produce antibodies?

Question 2

How does a vaccine prevent disease?

Question 3

What is immunological memory?

Question 4

mRNA vaccines (like COVID-19 vaccines) work by:

Question 5

Which of the following contributes to "herd immunity"?

Key Concepts Summary